This is because one patient exhibited prominent contracture of ankle and elbow joints, another patient presented hyperCKemia without definite muscle weakness, and the other patient showed minimal inflammatory cell infiltration on muscle pathology.
This protection was characterized by minimal inflammatory cell infiltration, inflammatory cytokine production, and demyelination in the CNS of treated animals.
In addition to the minimal inflammatory cell infiltration, multinucleated giant cells that might represent viral cytopathic effect were only occasionally seen.
Furthermore, the samples from the rats in Cluster 3 were represented by a histopathologic prototype characterized by minimal inflammatory cell infiltration in the centrilobular region, regeneration and degradation of the hepatocytes.
Interestingly, a high proportion of SCUBE2-positive tumors (11/12) were lymph node-negative and all STK32B-positive tumors (15/15) were smaller in size (T1-T2 tuminimalminimal peritumoral inflammatory infiltration was found in tumors with reduced CBX2 levels.
Shia et al. [ 123] reported that, in 60% of cases, the inflammatory infiltration was only minimal.
Histopathologic findings in kidney tissue from rats inoculated with U. parvum ranged from minimal changes to varying degrees of inflammatory infiltration that consisted of lymphocytes, plasma cells, macrophages and neutrophils.
The degree of lymphoplasmacytic infiltration (inflammatory infiltration) was classified as minimal (few inflammatory cells), moderate (1-2 margingin), and strong (>2 mm margin) according to the density of inflammatory cells.
Histological analysis demonstrated that autologous fascia promoted a relatively minimal inflammatory response and neovascularization but moderate collagen infiltration when compared to fenestrated porcine dermis and porcine collagen-coated polypropylene mesh [ 20].
On the basis of subcutaneous implantation in rat, PEG-D4 nanocomposite hydrogels elicited minimal inflammatory response and exhibited an enhanced level of cellular infiltration as compared to Laponite-free samples.
