In particular, in Calu-6 cells, gemcitabine caused a 1.3-fold1.3-folde in the population of cells in the G1 phase, from 50.5 to 64.1%, while DNA contents of cells treated with gemcitabine showed a minimal increase (+5.8%) at the G1 S region in A549 cells.
A CTTA-based surveillance strategy produced a minimal increase in mortality at 5 years (74.2% versus 73.9%) and a minimal reduction in average life expectancy (10 11 days) but with cost savings of up to £1248 per patient and net monetary benefit of £427 per patient (i.e. cost-effective; based on a willingness to pay £30,000 per life year).
The cost of the solution is a minimal increase in computation complexity at the receiver.
Also the fuel itself is a fair coolant, enabling high power density at minimal increase in stack weight.
Distances were measured as Euclidean, and a linkage method based on the minimal increase of intracluster variance at each linkage step was used (Ward 1963).
No apparent threshold value was observed in either agonist treatment, indicating a drastic increase in vasorelaxation occurred at a minimal increase of EC [Ca2+]i.
IDI and NRI showed at most minimal increase for variants with frequency greater than or equal to 0.005 and OR greater than or equal to 5. Since rare variants are present in only a minority of affected individuals, their predictive ability is generally low at the population level.
As shown in Figure 1C, HHT did not induce cell death by itself, except for a minimal increase in A818-4 and Pt45P1 cells at 24 h (the longest incubation time).
ADRB2 was also upregulated by clorgyline in our microarray data (2.1 and 1.7 fold at 6 and 24 hr, respectively; data for 96 hr was not available after filtering), although EZH2 expression showed minimal increase (1.0-, 1.2-, and 1.2- fold at 6, 24, and 96 hr, respectively).
Cutting plantations rapidly and persistently benefited native species for at least 14 years, with minimal increase in non-native plants.
