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Therefore, all reported colocalization ratios in the present study should be regarded as minimal estimations.
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Since detached cells, which are enriched in apoptotic cells, were not included in this measurement, the estimated percentage of apoptosis determined here is a minimal estimation of the true apoptosis levels.
The new signal, which has the minimal estimation residual in the least square sense, is adopted as the best estimation.
Based on this necessary condition, we propose an explicit optimal periodic schedule, which is rigorously proved to have a minimal estimation error at the estimation center while satisfying the transmission power and channel bandwidth constraints.
The stochastic origin ensembles (SOE) method was investigated as an imaging method for the DPI because only a minimal estimation of system response is required to produce images with quality that is comparable to common maximum-likelihood methods.
This approach makes phasor measurements, at generator & DER buses, available with minimal estimation errors.
The CRO value represents the minimal estimation of the matrix contribution to the analyte signal offset via the correlated standard deviation (~correlated sensitivity).
PPRT [ 18, 28]; MLPA [ 28]. ~: rounded; n: multiple of the minimal estimated CN; *: CN estimations based on ultra-deep 454 sequencing; nd: no data; blank: non polymorphic.
Consequently we conclude that our estimation is quite a reasonable minimal estimate.
The final minimal CN estimations for the samples range between 3 and 9 (Table 3, Additional file 1, Table S7).
Only in this single case, the HC-based minimal CN estimations can not be unambiguously interpreted and considerably deviates from 2 copies per diploid genome, consistently determined by 4 alternative methods.
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