Sentence examples for minimal effective concentration from inspiring English sources

What are the minimal effective concentration, EC50, maximum effect level, and does the effect level off at high exposure?

What is the minimal effective concentration, EC50, maximum effect level?

The effect is further limited by using the minimal effective concentration of the crosslinker, as determined by preliminary titration experiments.

If efficacy and adverse reactions occurred at similar doses, this raises concerns as to whether the minimal effective concentration was reached in all patients – no side effects might reflect noneffective drug concentrations.

AFM image showed that the minimal effective concentration of (1S,3S -isomer and (1S,3S -isomer inhibiting plandlet activation were 1R,3S -isomer−6 M, respectively.

*MEC, minimal effective concentration; ND, not determined.

Minimal effective concentrations (MECs), determined by radial diffusion assay, were generally lower than minimal inhibitory concentrations (MICs) determined by microbroth dilution.

For echinocandins, minimal effective concentrations (MEC) were defined as the lowest concentration of drug that led to the growth of small, rounded, and compact hyphal forms.

We evaluated the modulating activity of AZA and DAC (used at the minimal effective concentrations established with the above-mentioned demonstration of apoptosis) on the levels of acetylated histone H4 and H3K4me3 (as markers of euchromatin), H3K9me2, and H3K27me3 (as markers of heterochromatin) in whole cell lysates of AML1/ETO-positive and negative cells (Fig. S2).

Levels above the minimal tolerated concentration may result in serious toxicity, and levels below the minimum effective concentration will be subtherapeutic.

Evaluation of plasmatic concentration following injection of the different doses in rats revealed that the minimal effective plasma concentration of ketamine (approx. 200 ng/mL) was achieved only in a few animals at 25 mg/kg IP, which is the same plasmatic therapeutic concentration needed for treatment of neuropathic pain in humans [ 45].