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They all deviate considerably from the general, bacterial archaeal eukaryal nuclear, consensus structure or the bacterial minimal consensus structure (Fig. 1).
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For a pair-wise alignment against a consensus structure, output is as above except no consensus structure is produced.
Furin cleaves a wide range of proproteins at the consensus sequence Arg-Xaa-Lys/Arg-Arg-↓, and the minimal consensus sequence for Furin is Arg-Xaa-Xaa-Arg-↓.
The NFAT minimal consensus sequence is GGAAA A) or TGGAAAGT.
The minimal consensus ERE sequence is a 13 bp palindromic inverted repeat: 5'-GGTCAnnnTGACC-3' [52,53].
These resources generally had a low risk of bias, but there was minimal consensus among them.
Events (losses or gains) selected as diagnostic characters corresponded to minimal consensus regions.
The flanking regions around the minimal consensus sequence in the PCSK targets are less well examined.
In analogy to the consensus sequence, we further define a consensus structure.
Using the multiple alignment function of RSmatch, we generated a consensus structure for each structure group.
Structures are aligned, and a consensus structure is shown for each group.
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