The minimal test compound concentration causing ≥99% reduction of bacteria was defined as the MMC99.
Best et al. (265) investigated the tetrasaccharide 6′′-α d-glucopyranosyl-maltotriose as the minimal model compound for the amylopectin branch point and found that the addition of the extra residue provided more interresidue interactions.
Very minimal rainfall compounded with high evapotranspiration rates in this region causes limited availability of renewable water.
In order to arrive at the most optimal assay with respect to the signal window and minimal interference from compound autofluorescence, we compared the performance of ethidium bromide, the dye most commonly used in this assay, to ThO, in side-by-side titration experiments using an unlabeled version of the optimized APE1 substrate (Figure 1C).
Compared to a distance measure based on either the correlation or minimal degree, this compound distance compensates for biased results due to, for example, very high profile correlations or missing pieces of prior knowledge.
At high loading levels, DNA showed minimal increases in compounding torque, while MPP increased torque by over 20%.
The AFP model for skin sensitisation was built on the training set by using the following parameters: maximal number of rules for each chemical activity = 30; minimal number of compounds for a given rule = 2; maximal number of cuts for each axis = 5.
Short truncated compounds (minimal domain), chimerical constructions and improved sequence analogs have been reported.
The in-silico minimal set of compounds needed for the endosymbiont in order to produce all biomass components was predicted for both model versions (iCG238 and iMP240), using an optimization algorithm (see Minimal Medium Prediction in Methods section).
Although a number of preclinical studies showed very good efficacy of MEK inhibitors for reducing cancer cell proliferation and inducing apoptosis, patient responses in clinical trials have been minimal with these compounds as single agents.
