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Exact(10)
In patients with solid tumors low dose DAC showed only minimal clinical activity [ 20, 21].
These findings oppose a recent study by Abidoye et al, (2006) that reported minimal clinical activity in patients treated with lapatinib, who had recurrent or metastatic SCCHN.
Pateclizumab had minimal clinical activity by DAS28(4 -ESR but this did not reach statistical significance compared to placebo at Week 12.
In a recent clinical trial evaluating the efficacy of green tea extract (GTE) on prostate cancer, it was found that the GTE had minimal clinical activity [ 7, 8].
The minimal clinical activity of the cdk inhibitors as single agents is similar to that seen to date with tyrosine kinase inhibitors and angiogenesis inhibitors.
A phase II study of 35 patients with metastatic, castration-resistant prostate cancer revealed minimal clinical activity of Romidepsin (Molife et al. 2010).
Similar(49)
In two recent phase II trials in patients with refractory metastatic breast cancer, the EGFR inhibitor gefitinib showed minimal to no clinical activity (Baselga et al, 2005; von Minckwitz et al, 2005).
In a Phase I/II, clinical activity with minimal toxicity was observed at multiple dose levels in mutant BRAF tumors [9].
AJFAT = Ankle Joint Functional Assessment Tool FAOSS = Foot and Ankle Outcome Score; FADI = the Foot and Ankle Disability Index; FAAM = Foot and Ankle Ability Measure; 1 = Rozzi et al, 1999; 2 = Roos et al, 2001; 3 = Hale and Hertel, 2005; 4 = Martin et al, 2005; MCID = minimal clinical important difference; ADL = Activities of Daily living.
Given that HIPE is a minimal dataset with the primary objective of auditing overall clinical activity, these factors were not built into the original HIPE dataset.
"Does that mean your writing is a cold and clinical activity?" "No, never clinical.
More suggestions(15)
modest clinical activity
minimal clinical utility
minimal inhibitory activity
minimal clinical beat
minimal antimicrobial activity
minimal clinical toxicity
minimal clinical efficacy
minimal clinical value
minimal volcanic activity
minimal residual activity
minimal clinical improvement
minimal clinical presentation
minimal clinical significance
minimal osteoblastic activity
minimal clinical change
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