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A pharmacophore conveys minimal characteristics of the structures of the ligands which are critical for binding to the target.
Together, the minimal characteristics of surface markers still appear to be insufficient for defining the precise role of MSC and additional markers will be required for determining tissue-specificity, a selective MSC subpopulation, and the activation status of MSC.
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The expression of LTβR (as a minimal characteristic of FDC precursors), and of DRC-1 and CD21L (FDC-specific markers) was studied with both immunocytochemical staining (LTβR and DRC-1) and RT-PCR (CD21L).
A comparison of the minimal characteristic domain organisation of these groups of proteinases is shown in Fig. 1.
Minimal, known characteristics of cellular behavior are sufficient to show the networks presented here generate known phenomena.
Central schemes, such as the Kurganov–Tadmor (KT) family of methods, require minimal characteristic information, which makes them easily applicable to systems with an arbitrary number of phases.
Later Pierre formulated the principle of symmetry, which states the impossibility of bringing about a specific physical process in an environment lacking a certain minimal dissymmetry characteristic of the process.
We believe that the effect on the results of the patients dropping out was minimal because the characteristics of the followed subjects and those who dropped out were very similar.
Each time series of SWC was decomposed into 50 scale components using the Mexican Hat wavelet and later reduced to 5 group components with minimal impact on the characteristics of the signal.
These regions displayed characteristics of minimal mobile elements, which were defined as variable regions among the closest relatives in sequence composition and gene content between specific conserved flanking genes (Saunders and Snyder 2002; Snyder et al. 2007).
However, none of these species seem to share the characteristics of the minimal essential chicken MHC.
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