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The optimized rat tibial fracture model resulted in mainly transverse tibial mid-shaft fractures with minimal bone comminution and absence of surrounding soft tissue damage.
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Even though the prefixed IM could not provide rigid stabilization to the fractured bone, it could minimize the bone comminution during the fracture and at the same time could resolve the problem of post fracture limb shortening and rotation of bone fragments (Omerovic et al., 2015) in rats.
The slight comminuted fracture was observed in four animals and the other was without any bone comminution.
The presence of bone comminution, and the fracture bone alignment were immediately examined after the induction of the fracture until the 6th week.
The obtained radiographs were used for objective evaluation of the bone healing using criteria such as bone union, size of callus formation, degree of bone comminution, pin angulation, and radiograph callus index.
For bone comminution evaluation of all tibial fractures (n = 25), only four (16%) showed slightly comminuted fractures while the other twenty one (84%) were non-comminuted.
Moreover, it appears that fractured bone comminution in various degrees has been particularly difficult to control during fracture healing (Pei and Fu, 2011; Ghiasi et al., 2017).
Minimal soft-tissue contracture and minimal bone loss were encountered during reimplantation.
These include either high-energy fractures with severe bone comminution that may be further complicated through open injury, fractures in older people with poor bone quality and periprosthetic fractures.
Radiographic examination showed minimal bone resorption mesial and distal of the implant (Fig. 9).
This resulted in minimal bone augmentation relative to the functional needs of the definitive prosthetic rehabilitation.
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