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Exact(6)
A peptide composed of amino acids 15 29 was identified as a minimal binding region.
We previously proposed that DLC1 375–509 is the minimal binding region of tensin2.
Mass spectrometry of degraded fragments yielded a minimal binding region.
This result indicated that the repressive function of intron 1 maps predominantly to the 0.3 kb minimal binding region.
We initially identified cyclin D1 as a binding partner of BARD1 in a yeast-two-hybrid screen and defined the minimal binding region as the N-terminus of BARD1.
This ICpeptide, IC-G2736X (D2590-G2736)(Table 3), was also created by Tang et al., and encompasses the part of IP3R1 that encodes the minimal binding region for the expanded polyglutamine repeats in huntingtin, and likely the mutant ataxin proteins [ 52].
Similar(51)
Significantly, since the minimal binding regions do not overlap, the RNAP II CTD, CstF-50, and the BARD1 C-terminal domains could potentially all interact within the elongating transcriptional complex.
(B ) ITC-based mapping of the minimal AnkR_repeats binding region in the C-terminal regulatory domain.
Fondaparinux is a synthetic highly sulfated pentasaccharide which has a sequence derived from the minimal antithrombin binding region of heparin.
Further truncations from the N-terminus revealed a minimal membrane binding region between aa 93 and 107 as indicated by a four-fold decrease in liposome binding upon removal of these 15 amino acids.
To enable us to distinguish effects due to construct length from effects due to the introduction of interchain disulfide bonds, we created a corresponding set of mutants based on the minimal IKKβ binding region NEMO-44 111, NEMO-44 111NEMO44–111(designatedMO44–111(des2C/C54), NEMO44 111 des3C/L107C), aNEMO44 111 des2C/C54C54/L107C).
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