Sentence examples for minimal alterations of from inspiring English sources

Given that minimal alterations of the histone H3 tail peptide drastically reduce its affinity for PHD HD1 complexes, we surmised that we might be able to identify small molecules that bind to these histone pockets and interfere with their binding to the histone H3 tail.

Pillars demonstrated minimal alteration of the inner retinal architecture, and thus appear to be the most promising approach for maintaining close proximity between the retinal prosthetic electrodes and target neurons.

Among the various cluster ions that have developed over the past decade, pulsed C60+ was selected as the primary ion because of its high secondary ion intensity in the high mass region, its minimal alteration of the surface when operating within the static-limit and spatial resolution at the ∼μm level.

Therefore, cost efficient approaches that introduce minimal alteration of the ecosystem are desirable.

The intravenous cannula was removed on day 7 because of minimal alteration of the vein, no thrombophlebitis developed.

The severity of the CNS disease ranges from mild mental retardation with minimal alteration of cognitive function to severe and rapidly progressing disability and death.

An early work replaced Met121 in azurin with all other 19 amino acids with minimal alteration of the T1 character of the copper center.

Recent data support the importance of infection and inflammation even in minimal alteration of cognitive function in patients with liver failure and features of systemic inflammatory response syndrome [ 37].

The diaphragm was chosen as a representative parietal pleural tissue because at necropsy it could be removed within minutes of sacrifice with minimal alteration of the visceral lung surface.

A somewhat indirect but readily accessible approach is isotopically labeling the protein (C, N, and H for most nonexchanging positions), creating a "Born Oppenheimer enzyme", which slows the fast vibrations in question with minimal alteration of the electronic potential surface.

These mutants had relatively little effect on the ability of the tDNA to block progression of SUT467 (lanes 2 and 3 compared to wild type in lane 1) as evidenced by a minimal alteration of the ratio of normal to extended transcripts.