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We hypothesized that choline would be well tolerated with minimal adverse events.
Among studies observing adverse events, four RCTs reported minimal adverse events,34, 38, 40, 43 whereas two RCTs reported no adverse events,32, 42 compared to appropriate control groups.
Apart from achieving the projected numbers, achieving them with minimal adverse events (AEs) is essential.
The main goal of procedural sedation and analgesia (PSA) is to give patients some relief from both pain and anxiety with minimal adverse events.
Palliation with minimal adverse events remains the cornerstone of management.
Sustained uptake of MC will require performance of the procedure with minimal adverse events.
Palliative care with minimal adverse events is the cornerstone of management.
While the risks of allergy to oral iodinated contrast are minimal, adverse events do occur [ 20, 21].
Theoretically, combinations of conventional chemotherapy with targeted biological therapy for specific patients are especially appealing because such approaches may improve clinical efficacy with minimal adverse events.
Liver biopsy is not without risk; however, the current data show that when performed by experienced personnel, it can be performed with minimal adverse events.
34 Interestingly, in the dose-escalation study reported by O'Brien et al, rituximab doses of 500 to 1500 mg/m were associated with minimal adverse events.
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