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They were proposed for the short-term prophylaxis at the beginning of the cluster period instead of steroids (defined also as transitional therapy) or for the short-term prophylaxis of mini cluster.
Group each mini cluster together by summarizing them with one keyword.
A symptomatic treatment alone should be limited, in the episodic form, to active phases of short duration (mini cluster).
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When adaptor complexes (recombinant protein A/G molecules loaded with both anti-His and anti-EpCAM IgGs) were added to the mix, TECs were tethered to the hydrogel and formed 3-D mini clusters.
The most studied neurotoxin cluster in proteolytic C. botulinum is termed the ha plus/orf-X minus cluster.
Four of the 19 strains (21%, including B38) of the MALT lymphoma PAI minus cluster, contained HacII prophage-like sequences.
The 16 type B strains gave an almost identical hybridisation pattern, with all neurotoxin genes present in a ha plus/orf-X minus cluster.
The probe designed to be specific for cntR/A1 gave a positive result with all strains that possessed a neurotoxin gene in a ha plus/orf-X minus cluster.
For example, the present study has confirmed earlier reports [ 18, 38] that in type A1 strains, the neurotoxin genes may be located in a ha plus/orf-X minus cluster or in a ha minus/orf-X plus cluster.
Twelve of the fourteen type A1 neurotoxin strains tested contained the ha plus/orf-X minus cluster, but in two strains (F9604A and MUL0109ASA) the type A1 neurotoxin gene appears to be in a ha minus/orf-X plus cluster.
It is likely that these strains possess a type F gene in a ha minus/orf-X plus cluster, plus a type B gene in a ha plus/orf-X minus cluster.
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