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Session duration ranged from 30 to 120 min; three studies did not report the session duration [ 31, 44, 50].
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Dopexamine increased right ventricular ejection fraction significantly more than did iloprost at a dose of 0.68 μg/kg per min. Eight studies investigated the effects of dopexamine on regional perfusion.
Primary outcomes were peak muscle strength in five studies (from four citations 16 37 38 40), peak VO2 in five studies (from four citations 37 40), peak workload in five studies (from four citations 16 37 38 40), 6 min walking test (6MWT) in four studies 16 39–41 and HRQoL in three studies.
Only three studies have reported an EU duration in excess of 5 min [23, 27, 28].
Three studies [ 20– 22] used the ICG plasma disappearance rate or retention rate at 15 min [ 56].
Three studies reported VO2max in mL/min, 28 mL/kg per minute, 31 or L/min, 32 and one study reported aerobic capacity as L/min.
61 min Three substitutions.
90 min Three minutes of extra time.
90+1 min Three minutes of added time.
Oxygen was administered at rest in three studies (Bruera et al, 1993; Booth et al, 1996; Philip et al, 2006) and during a 6MWT (6-min walk test) in two studies (Bruera et al, 2003; Ahmedzai et al, 2004).
Out of all quantitative studies, patients' refusal was mentioned in eight studies (min 2 max 93 refusals).
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