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rCBF was measured again during the last 5 min of infusion and at 75 80 min after start of hαCGRP/placebo infusion.
Standard adenosine protocol was a continuous infusion at 100 μg/kg/min for 1 min and then 140 μg/kg/min for 4 min, with tracer injection after 3 min of infusion.
Thus, during 7 h of GTN-infusion in healthy subjects the mean dilatation of the radial artery was 36% after 5 min of infusion of 0.5 μg/ kg min) and remained stable over time [25].
Mean arterial blood pressure (MAP) was immediately slightly reduced by PDNO and remained significantly lower compared to vehicle (83 ± 3 vs 94 ± 3 mmHg, p = 0.02, after 6 h and 15 min of infusion, Table 1).
(2) Cortical CNQX must abolish CRs within 10 min of infusion.
Mice for control experiments were bled retro-orbitally under anesthetics after 15 min of infusion of vehicle solution, ticagrelor or cangrelor.
Similar(28)
The first sample will be taken 1 minute prior to the infusion of the antibiotic and then at 5 min (end of infusion), 20 min, 60 min, 210 min and 360 min respectively post commencement of the infusion.
Piperacillin-tazobactam (infused over 20 min) - the first sample will be taken 1 minute prior to start of the infusion and then at 20 min (end of infusion), 40 min, 60 min, 210 min and 360 min respectively post commencement of the infusion.
For admission to the Cortex+Nucleus group, subjects must have satisfied the following criteria: (1) Both cortical and nuclear muscimol abolish CRs for at least one 10-trial block, and to ≤10% within 50 mins of infusion.
Vmean, rCBF and CBV were measured before and after 20 min of GTN infusion and 60 min after the infusion.
In the second study [ 46], treatment success was defined as clinical seizure cessation after infusion without need for rescue medication within 20 min of the infusion.
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