We retrospectively collected 109 migraine patients from those reviewed who had visual evoked potentials (VEPs) recordings (6 blocks of 100 sweeps, 15 min of arc cheques, 3.1 repetition rate) and information about parental history of migraine.
To find out whether ketogenic diet alters VEP habituation, we recorded VEPs (3.1Hz reversal rate, 15 min of arc checkerboard visual pattern) before and during ketogenesis, as confirmed by urinary sticks, in 15 migraine patients.
Sixteen interictal migraine without aura patients (MO, ICHD-II code 1.1) underwent VEPs (right eye stimulation, 600 sweeps, 3.1Hz reversal rate, 15 min of arc check) and median nerve SSEPs (right stimulation, 500 sweeps, 4.4 repetition rate, 1.2 motor threshold) recordings, before and during ketogenesis, confirmed by urinary sticks.
We used a nonlinear numerical tsunami model that takes seabed friction and Coriolis force into consideration, where one grid size is 1 min of arc (along longitude and latitude), the time difference is 3.06 s, and the system of coordinates is spherical.
We cannot thus rule out that the spatial frequency of 2 cycles/degree (15 min of arc) used in our study may have prevented us from detecting a significant impairment of long-range lateral inhibition in migraineurs which might have been possible with lower spatial frequencies.
We recorded pattern-reversal visual evoked potentials (VEP: 15 min of arc cheques, 3.1 reversal per second, 600 sweeps) and measured amplitude and habituation (slope of the linear regression line of amplitude changes from the 1st to 6th block of 100 sweeps) for the N1-P1 and P1-N2 components in patients and, for comparison, in 30 healthy volunteers (HV) of similar age and gender distribution.
As measured by mean deviation from the target, fixation and pursuit accuracies were improved by 8.3 and 3.3 min of visual arc, respectively (35.8% and 6.8%), for inter-phosphene spacing of 1.9°.
A robust induction of both Arc and c-fos mRNAs was observed in the hippocampus, with a peak at 60 min for Arc mRNA in either wild-type (Figure 5H) or hip-eEF-2K-tg mice (Figure 5I) and a peak at 30 min for c-fos mRNA in either wild-type (Figure 5J) or hip-eEF-2K-tg mice (Figure 5K).
The verniers consisted of two vertical bars of 10' (arc min) length.
Dot Verniers consisted of three dots with a radius of 2' (arc min) and with a distance between the upper and lower dot of 20' (Figure 1A).
The detection system can cover a large range of scattering angles [5°, 165°] by using an array of 64 He-3 position-sensitive detectors provided with 10 arc min of a Soller collimator in front of each detector.
