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To this end, rats received 0 or 15 mg/kg BMOV intravenously 30 min before renal artery clamping, and we measured renal oxygenation and renal function up to 90 min of reperfusion.
30 min before renal clamping [ 6, 14].
Baicalin was intraperitoneally injected 30 min before renal ischemia.
Saline-treated animals received intraperitoneal injections of 1 mL 0.9% sterile NaCl 30 min before renal clamping.
Intralipid group (n = 7), Group I: 30% intralipid was intravenously infused at a dose of 2 ml/kg for 30 min before renal ischemia.
Baicalin-treated rats received intraperitoneal injections of baicalin (Sigma), diluted in sterile saline to 1, 10, or 100 mg/kg body weight 30 min before renal clamping.
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For this purpose, we administered intravenously EDTA 30 min before the induction of renal Isc, obtained by clamping the right renal artery and the right renal vein.
However, higher doses of EPO (4,000 IU/kg given 30 min before LPS) attenuated the renal dysfunction (decline in glomerular filtration rate), which occurred at 16 hours after injection of low-dose LPS (2.5 mg/kg intraperitoneally) in mouse [ 10].
Pre-treatment of animals with Naringin, 60 min before Fe NTA administration, markedly attenuated renal dysfunction, morphological alterations, reduced elevated TBARS, and restored the depleted renal anti-oxidant enzymes.
as well as with trimetazidine (3 mg/kg, i.p ., 30 min before Fe-NTA administration markedly attenuated renal dysfunction, reduced elevated TBARS, restored the depleted renal antioxidant enzymes and normalised the renal morphological alterations.
30 min before they were subjected to bilateral renal ischemia.
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