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4D gated MR images of the three datasets (0.5, 1.0 and 5.0 min acquisition time) were reconstructed iteratively.

PET scans were performed 55 and 40 min after i.v. injection of the tracer (15 min acquisition time, 1 bed position, 3D mode).

Acquisitions at day 1 and 4 were performed using 15 min scan time, while 30 min acquisition time was used for imaging at days 5, 6, and 12. Acquisition duration was varied over time as we aimed to perform acquisition in realistic clinical conditions.

The total number of decays (Ntot) simulated for each phantom configuration and corresponding activities (assuming in each case 5 min acquisition time) are listed in Table 4 (Ntot was selected so that the total number of photons detected in PW was more than 15,000 in order to ensure errors are < 1%).

With the exception of 99mTc, all tested radionuclides provided optical signals with good sensitivity with 1 5 min acquisition time (Fig. 1A).

The column was maintained at 40 °C with a 0.6 mL/min flow rate and 5.5 min acquisition time.

P NMR spectra were first obtained (100 free induction decays (FID); 1 min acquisition time) without proton decoupling.

Using a simple chloroform-based extraction, we obtained classic low-field triglyceride spectra from typically a 10 min acquisition time.

C NMR spectra were obtained (200 FID; 3 min acquisition time) from a 66° radiofrequency pulse repeated every second (25,000 Hz spectral width).

The final SMRTbell libraries were bound to PacBioC2 polymerase and sequenced on PacBio RS using C2 sequencing chemistry and 2 × 45 min acquisition time.

Total body images of 10 min acquisition time were made at 40 min post (start of) injection (p.i .. Static spot views were obtained at 1, 3 5 and 24 h p.i. and also at 7 h p.i. in most cases.