Sentence examples for mimics the transition from inspiring English sources

The structure of the first mutant, D330N, which is threefold more active than the wild-type enzyme, was determined with phosphate in the active site, or with aluminium fluoride, which mimics the transition state.

X-ray crystallography discloses that the nitro group well mimics the transition state occurred in the hydrolysis catalyzed by CPA, that is, an O,O′-bidentate coordination to the zinc ion and the two respective hydrogen bonds with Glu-270 and Arg-127.

Green arrow marks the excitation by a 532 nm laser beam, the red arrow represents the optical transitions involved in the zero phonon line (637 nm), the brown arrow represents the nonradiative transition, the black double arrow indicates the MW transitions, while the broken arrows symbolize the intersystem transitions (arrow thicknesses mimics the transition strengths).

In the second part, we focus specifically on the transition from asters to stars, as it mimics the transition from lamellipodia to filopodia in cells.

The human TDP1 vanadate complex structure has a trigonal bipyramidal geometry that mimics the transition state of hydrolysis of a phosphodiester bond [ 8].

This pattern mimics the transition of bilateral-to-radial symmetry suggesting a role for the spatiotemporal dynamics of auxin in symmetry establishment.

Implication for inhibitor design by mimicking the transition state is also illustrated for both glycoside hydrolases and glycosyltransferases.

Described here is the asymmetric synthesis of iminosugar 2b, a Lipid II analog, designed to mimic the transition state of transglycosylation catalyzed by the bacterial transglycosylase.

Based on a strategy previously reported by us, we have synthesized d-xylo configured cyclohexenephosphonates designed to mimic the transition state of the sialidase reaction.

We probed rhomboid proteases with reversible, mechanism-based inhibitors that allow precise kinetic analysis and faithfully mimic the transition state structurally.

Here, we report the high resolution crystal structures of MurD in complexes with two novel inhibitors designed to mimic the transition state of the reaction, which contain either the d-Glu or the l-Glu moiety.