Sentence examples for mimics the pathophysiological from inspiring English sources

For this purpose, we used a 3-dimensional multicellular spheroid model that mimics the pathophysiological conditions and complex architecture of solid tumors [4].

Many models exist but there is no consensus on which best mimics the pathophysiological and clinical condition [ 38].

Although experimental endotoxemia in young humans without any co-morbidity mimics the pathophysiological changes in septic patients in many ways, important differences also exist.

In a rat model of periventricular leukomalacia, an injury that mimics the pathophysiological findings of SAE, treatment with APC was associated with less endotoxin-induced white matter and myelination deficits.

Toxicological studies using Boston CAPs in dogs with induced myocardial ischemia, an animal model that mimics the pathophysiological effects associated with IHD, demonstrated increased ST-segment elevation and impaired myocardial blood flow in response to PM2.5 CAPs exposure (Bartoli et al. 2009; Wellenius et al. 2003).

To investigate whether the OMV-induced lethality in mice was related causally to SIRS, sublethal doses of OMVs (1, 2, and 5 µg) were injected intraperitoneally three times, as shown in Fig. 3A, to mimic the pathophysiological conditions under which OMVs are secreted continuously.

Intravenous injection of purified histones in mice elicited thrombocytopenia, neutrophil migration, and organ failure mimicking the pathophysiological signature of sepsis [ 9].

These findings are compatible with a causal relationship between altered dopaminergic neuromodulation, so-called "aberrant" salience within the MTL, and the inability of the mesolimbic system to respond differentially to novelty and familiarity, which closely mimics some of the pathophysiological features of schizophrenia (Heckers 2001; Lisman and Otmakhova 2001; Lodge and Grace 2007).

In the past, leukotrienes have been shown to mimic many of the pathophysiological processes in allergic airway disease [ 12, 13] and since leukotriene C4 is renowned for its potent bronchoconstricting action, it was chosen as bronchoconstrictor in our study.

Although a variety of models based on different aspects of the pathophysiology of pre-eclampsia exist [ 39, 40], no model has been able to successfully mimic all of the pathophysiological features of pre-eclampsia or to accurately replicate the first trimester origin of the human condition.

Of note, 1 1 molar ratio of OA/PA with a final concentration of 0.4 mmol/L mimics the high fatty acid pathophysiological state [34], [35].