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Serum depleted media (0.5% FBS) was added to the lung cancer cells only, as this mimics more closely physiological conditions.
26 The use of whole blood has an advantage that it mimics more closely the in vivo conditions.
Importantly, we could show beneficial effects of hNPC on improved renal function in a mouse model of chronic progressive renal injury that mimics more closely CKD in humans.
We further evaluated the effects of drugs on sodium currents using a voltage-clamp protocol that mimics more closely the myotonic condition (Fig. 3).
Recently, low-dose endotoxin animal models have been described that result in a hyperdynamic circulation that mimics more closely the circulatory changes that occur in human clinical sepsis [ 19].
While different hybrid duplexes exhibit different stabilities or susceptibilities to different RNases, serum comparison mimics more closely an in vivo environment and allows direct comparison of each hybrid square.
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So the researchers also tested a second concoction chosen to mimic more closely what an average child might reasonably consume every day.
Phosphoproteins mimic more closely the physiologically relevant PP substrates, but their preparation is technically demanding.
By mimicking more closely the structure and composition of HM fat globules, this novel IMF concept with Nuturis® may have metabolic and digestive properties that are more similar to HM compared to Control IMF.
We have developed three-dimensional (3D) cell culture models of immortalized cells from NF1 PNs and of control Schwann cells (SCs) that we believe mimic more closely the in vivo condition than conventional two-dimensional (2D) cell culture.
Trimeric HIV-1 envelope glycoproteins (Env) are now being evaluated instead of monomeric gp120 as vaccine antigens because they mimic more closely the spikes expressed on the surface of virions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com