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Mimics can be grouped as parenchymal, vascular, biliary and peripancreatic.

The supramolecular enzyme mimics can be readily constructed by self-assembly which is an efficient strategy for generating highly-ordered structures with complex and hierarchical architectures to mimic the biopolymers.

If further studies determine these motifs directly contribute to either the cellular localization or, for STAM-1/2, proper ER export, this would provide support for the idea that ER export signals or their mimics can be used not only to facilitate ER export, but also to promote interaction with COPII vesicles to mediate specific antagonism of the secretory pathway.

miRNA oligonucleotide inhibitors or mimics can be targeted to specific tissues using relatively non-toxic delivery vehicles.

Even though siRNAs, and in a similar way miRNA mimics, can be stabilized through chemical modifications, their size still demands complex vehicles in order to ensure delivery to different tissues in vivo.

They are of immediate interest for the structural characterization of the diverse functional states passed through during the ribosomal elongation cycle and phenomena related thereto, 9 20 where mimics can be useful for A- and/or P-site substrate occupation.

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Similar(53)

Targeting of these miRNA-mimics can be augmented through the use of lenti-, adenor, or adeno-associated viruses (AAV) [ 19, 20, 65].

Similarly, a 'K36me1 mimic' can be made on H3.3 to prevent dimethylation [ 46]. me = Methyl ac = Acetyl un = Unmodified Relative turnover of various post-translationally modified peptides from H3.1, H3.2 and H3.3 variants with respect to each other.

Taking advantage of ΦC31 attP sites, gene trap cassettes in MiMIC can be easily swapped with any DNA sequence flanked with attB sites by ΦC31 recombinase, allowing further gene modifications and genome editing [ 33].

(ii) The fact that miRNA antagonising molecules (antagomiRs/antimiRs) and miRNA mimics (miRNA mimetics) can be used.

I'm also a pretty good mimic and can be very silly at times, dissolving into giggles easily.

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