Sentence examples for mimics based on from inspiring English sources

In the present study, phosphatidyl inositol mimics based on a β-glucoside scaffold have been synthesized as Akt inhibitors.

We have used a conceptually novel way to construct antibody mimics based on the binding of a noncatalytic enzyme to its substrate.

Synthetic C-terminal amidated cationic ferrocenoyl peptide bioconjugates Fc-Orn-Orn-Orn (1) and Fc-Tyr-Orn-Orn-Orn (2) were rationally designed as superoxide dismutase (SOD) mimics based on the structure of the iron SOD from Escherichia coli.

In an attempt to improve inhibitory potency, we designed new NAD mimics based on a single adenosine moiety harboring a larger derivatization attached to the C8 position and a small group at the 5′ position.

Using "monobodies," small antibody mimics based on the fibronectin type III domain, as the target-binding proteins, we demonstrated the effectiveness of our method by separating the active form of the estrogen receptor α ligand-binding domain (ERα-LBD) from a mixture of active and misfolded species and by discriminating two different conformations of ERα-LBD bound to different ligands.

Of these three morphs, Androchrome females are considered to be "male mimics", based on their blue colouration and melanic patterning which is identical to males [24].

Ten of these genes were also upregulated by oxidative stress mimic based on induction patterns during exposure to 4 mM H2O2.

As shown in Figure 7A, miR-34 restoration in Kato III cells rendered the cells 2-3-fold more sensitive to the four chemotherapeutic agents, as compared with the cells transfected with the control mimic, based on IC50 data.

Side-by-side comparison of the apo-structure of the D. rerio TCP-domain of CPAP (left) with the structure of an engineered peptide-assembly mimic based on Borrelia OspA (right) that is used to study β-rich self-assemblies (PDB code 2FKJ, chain A).

As with Cu II -Ybt, early SOD mimiCu II -Ybtsearly Cu(II)-SODcomimicss.

The findings of this study also have significant implications in the design of CDK4 mimic structures based on CDK2.