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Adaptating HSEs to study wound reepithelization has demonstrated several key responses including cell proliferation, migration, differentiation, growth factor responsiveness and protein expression that mimic the response to wounding seen in human skin [7].
A shift in the wearer's balance, indicating their desire to take, for example, a step forward, triggers the suit to mimic the response that the joints would have if they were not paralysed.
A homogenized material model was then calibrated to mimic the response of the cell across the range of stress states that were examined.
Novel therapeutic strategies that promote wound healing seek to mimic the response of the body to wounding, to regenerate rather than repair injured tissues.
The results provide insight into the design of materials intended to mimic the response of a certain class of biological tissues with stiffening characteristics such as chordae tendineae.
The first closed loop control experiment has successfully demonstrated that the digital control system can be programmed to mimic the response of the analogue control system.
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However, dichlorvos exposure does not fully mimic the responses to infection.
Thus, although some responses of regular exercise mimic the responses of pathological stimuli (e.g. cardiac hypertrophy and electrical remodelling) the signalling pathways and eventual outcomes of physiological and pathological stimuli are not usually the same.
To investigate the activating or co-stimulating properties of TLR3 on γδ T cells, a TLR3 ligand was added to the cells at the re-stimulation stage to mimic the responses to specific and non-specific stimulations.
Therefore, IL-1β appears to mimic the responses of the carotid body to hypoxia and may, therefore, act in an autocrine manner to enhance the peripheral chemoreceptor drive during systemic inflammation.
In contrast, three-dimensional culture models of human skin, lung, cardiac tissue and liver faithfully mimic the responses of living tissue, and can be used to predict how these tissues might respond to potential therapies (Bhatia and Ingber, 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com