Sentence examples for mimic the development of from inspiring English sources
Strikingly, upon further development, the PASE exhibits cellular and molecular features that mimic the development of the posterior primitive streak (PS), with a requirement for SNAI1 to fully deploy epithelial-to-mesenchymal transition and cell dissemination.
The Wayne model (Wayne & Hayes, 1996) for example, uses gradual oxygen depletion to mimic the development of the granuloma, and was recently employed by Muttucumaru and colleagues (2004).
Genetically-engineered mouse models (GEMMs) of cancer have been constructed to more closely mimic the development of human disease in a predictable manner [ 24].
To mimic the development of human inflammation-associated lung fibrosis in mice, we trans-nasally administered bleomycin to gender-matched mice (8 12 weeks of age) harbouring gp130 mutations that bias intracellular signalling either towards the Stat1/3 or Erk1/2 signalling pathways in gp130 757F mice or gp130 ΔStat mice, respectively (Tebbutt et al, 2002) (Supporting Information Fig S1).
In surgical models of OA that mimic the development of posttraumatic OA, the cartilage damage caused by the surgery precedes changes in the subchondral bone.
Here we present a novel transgenic mouse model, APPSLPS1KI that closely mimics the development of AD-related neuropathological features including a significant hippocampal neuronal loss.
Another commonly used method for neural induction is via EB formation in a chemically defined system including a minimum medium, which mimics the development of neural ectoderm cells in morphology and gene expression profiles[3], [5], [37].
This phase mimics the development of a predictive biomarker (see next section).
Since the model used here mimics the development of emboli in the microvasculature, future testing will assess nanoSTATs' ability to treat thrombosis in larger vessels, which are representative of clinical situations such as myocardial infarction or thrombotic stroke.
For in vitro studies, we chose a method of neurogenesis from adherent-monoculture of ESC, which sequentially mimics the development of cortical neurons over the course of 21 days of differentiation [ 74].
This model accurately mimics the development of human ACS as indicated by an increasing IAP and plateau pressure (Ppl) with a decrease in oxygenation (P/F ratio), CO, and UOP.
