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Cartilage mean T2 values in milliseconds were calculated for all conditions using OsiriX software (version 3.7.1) [ 41].
In both paradigms, spatial accuracy measures of primary saccade gain (saccadic amplitude divided by target amplitude) and final eye position (the longest stable period of fixation after any corrective saccades had been made, expressed as gain) as well as latency to perform a correct antisaccades (milliseconds) were calculated.
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The millisecond latencies were calculated when the movement artifact associated with straining appeared on the crural EMG and then the time to the first muscle action potential was measured as an index of latency.
Assuming that the time interval between the adjacent measurement points ( cm) is 0.5 milliseconds ( milliseconds), then is calculated from (3) as follows: (4).
For the analyses of HRV, the times in milliseconds of occurrence of two consecutive R waves in the ECG waveform (RR) were calculated on a beat-to-beat basis.
Thresholds in milliseconds for each frequency tested (500, 1000, 2000, and 4000 Hz) and for click stimuli were calculated.
Errors were calculated for each cell as the width of each half cycle in milliseconds divided by the actual half-cycle width of the stimulus (1.67 ms for 300 Hz) and converted to percentage.
These values were calculated for three different phases, based on the angular knee displacement: 300 milliseconds before initiating the movement (P1), from P1 to the knee flexion peak (P2), and from P2 up to the total knee extension (P3).
RTs were calculated as the time of the spoken response minus the onset of the number pair in milliseconds (msec).
Movement time was measured in milliseconds and throughput was calculated in accordance with the equation recommended by Soukoreff and MacKenzie [ 51].
Cycling-off timing-difference in milliseconds (TCYC-OFF) was calculated between time points for early decrease in Paw and 30%% decline from EAdi peak.
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