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Exact(6)
Techniques based on microarray technologies can simultaneously measure thousands to millions of loci in the genome for DNA copy number changes.
In large-scale studies, when thousands to millions of loci are measured, the threshold to declare any locus significant is typically based on a more stringent level of significance (e.g. Bonferroni correction or similar) in order to minimize the possibility of false positives, therefore we have displayed the power at two such thresholds.
As variants in cancer samples are typically rare and millions of loci are analyzed, specificity is a major concern.
Therefore, the scalability of GeD to larger eQTL data sets containing thousands or even millions of loci remains to be tested.
In these experiments, it is common to observe hundreds of thousands or even millions of loci in the DNA of a studied sample that differ from the reference genome.
A demonstration of shifts in allele frequency confirms that evolution has occurred – but genomes contain thousands to millions of loci, making shifts at some of them inevitable in all situations.
Similar(54)
For FST, we used the 95th quantile to determine loci with 'low FST' (i.e., ~95% of loci get classified as 'low FST'low
Use the method of Loci.
Transcripts are named by their respective locus, version (isoform) number, raw RPKM and precursor flag; e.g. Locus1v2rpkm3.45_PRE is the 2nd most abundant isoform of Locus 1 with an RPKM of 3.45, marked as a precursor transcript.
Using the top 10000 CETS markers, corresponding roughly to the top 5th percentile of CETS loci, we developed a method capable of quantifying the proportions of neurons and glia based on generalized and disease non-specific cell type epigenetic markers as a proxy for cellular proportions.
Intentionally or not, 24th Street has become a sort of locus for unusual parking arrangements.
Related(20)
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millions of users
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