Epidemiological studies suggested a number of congeners are simultaneously detected in serum, breast milk and adipose tissue in humans [6], [8], [26], [27].
For lipid-adjusted PCDFs, a different order was observed: placenta > maternal blood > cord blood > breast milk > adipose tissue.
Suzuki et al. (2005) reported relative concentrations of lipid-adjusted PCDD TEQs in the following maternal compartments: placenta > maternal blood > breast milk > adipose tissue > cord blood.
This allows comparison across various matrices, such as blood, breast milk, and adipose tissue.
Similar results are obtained from blood, serum, cord blood, breast milk, and adipose tissue if measurements are normalized to lipid (Hites 2004).
BPA and TCS have been detected in the blood, breast milk, urine, adipose tissue, liver, and brain of most human volunteers [ 9– 21].
As these compounds are lipophilic, they and their metabolites, have been found not only in blood, but also breast milk and adipose tissue.
These data, along with the results from previous studies of human postnatal blood, breast milk, and adipose tissues, suggest increased exposure of humans to PBDEs at every stage in life during the past decade.
Its principal metabolite is dichlorodiphenyldichloroethene (DDE), which, given its persistence and ubiquity in the environment, is presently found in environmental and human biologic samples (i.e., serum, maternal milk, and adipose tissue) (Turusov et al. 2002).
Finally, hair samples may also prove useful as a screening media to identify individuals or groups of individuals with high levels (e.g., special populations), ultimately allowing for more targeted and efficient studies using more traditional matrices, such as blood, breast milk, or adipose tissue.
