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It is encouraging to see that data from our engraftment studies demonstrated that the cartilage progenitor population can migrate to its specific milieu within the developing limb.
A pro-inflammatory milieu within the visceral fat, perhaps through increased free fatty acids, might increase the risk for loss of tolerance to the antigens, favoring chronic inflammation.
Thus, ruling out the direct damage to neurons due to toxicity, the other significant way by which neuronal death can occur is due to the generation of an inflammatory milieu within the brain.
The precise mechanism through which this occurs is unclear at present, but it is possible that the cytokine milieu within the tumor promotes the generation of Treg recognizing tumor-associated antigens.
Zinc has been reported to possess immunomodulatory activities [53], and it is possible that modifications of the cellular milieu within the mucosal tissues render the animals resistant to infection.
Because our study focused on the measurement of serum biomarkers, we can not know whether the patterns of peripheral inflammation reflect a "spill-over" of the local inflammatory milieu within the lungs or represent a synchronous, systemic molecular diatheses associated with either airway or parenchymal disease.
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Rather than being the divine milieu within which the self lives, the divine is only alive within the self.
So long as one assumes each item of a DV criminal sentence is intended to reduce recidivism, then the aging process should be seen as an important part of the milieu within which the DV criminal sentence is operationalized.
An important key to understanding stem cell activity and persistence in adult organs is the determination of the physical microenvironment and molecular milieu within which the stem cell resides (stem cell niche), and the determination of the conditions that allow for stem cell expansion or directed differentiation of stem cell progeny.
The generation of distinct chemical milieus within the body is essential for metazoan development.
In addition, approaches that act to alter the cytokine milieu within tumours, changing the microenvironment from one that is pro-tumour to one that is non-conducive to tumour growth are beginning to make an impact.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com