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Local inflammatory milieu provided by 3D-arranged MSCs in co-cultures induces a decrease in monocyte migration as compared to monolayer cells.
The survival and growth of a particular tumour cell are significantly affected by the local milieu provided by a particular organ environment (Fidler et al, 1994).
Since these processes take place soon after fertilization, the sex of the embryo and its physiological milieu provided by the mother can be determined close to fertilization.
Compared to 2D monolayer cells, local inflammatory milieu provided by 3D-arranged MSCs in co-cultures induces a decrease in monocyte migration.
Compared to 2D co-cultures, local inflammatory milieu provided by 3D-arranged MSCs reduces monocyte migration and this effect was mediated, at least in part, by reduced levels of IL-6 and MCP-1.
Moreover, a lower incidence of RA has been described during pregnancy, likely to be due to the anti-inflammatory milieu provided by elevated concentrations of circulating hormones, such as estrogen, corticosteroids and progesterone [ 48].
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A highly structured therapeutic milieu is provided by group workers, who are trained in cognitive behavioural and non-violent resistance techniques to promote social-emotional competence with children.
This nonpolar milieu might be provided by detergent molecules surrounding the protein or by the neighbouring helix residues of the ICD itself.
Not only those interactions are context-dependent and thus cannot be understood by keeping cells in an inappropriate milieu, like that provided by 2D-cultures, but also they follow nonlinear dynamics which make impractical modeling processes with more than two variables.
The social milieu provides the context for the organism's survival, endurance, and adaptation.
These antibiotics could reverse the favorable local milieu for anaerobic growth provided by other Gram-negative aerobes [ 24, 25].
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