Sentence examples for milieu necessary for from inspiring English sources

On the basis of the current literature we propose that neuroprotection by activation of anti-apoptotic mechanisms as well as improvement of the trophic milieu necessary for endogenous repair processes may be more important mechanisms underlying the improved functional outcome after stem cell treatment.

In these cases, inflammation caused by food could create the pro-inflammatory milieu necessary for the induction of migraine by other triggers.

In the silica-induced model, mRNA expression of Ym1 in the lung increased significantly in wild-type mice consistent with alternative activation, but did not increase in silica-exposed IL-4R null mice, indicating that a Th-2 milieu was necessary for alternative activation and fibrosis [ 162].

The cytokine and chemokine milieu of the joint is necessary for the initiation and the perpetuation of inflammatory arthritis.

The reason for this mucus phenotype is not understood, but an optimal local ion milieu is believed to be necessary for normal mucus expansion and organisation.

These findings indicate that the tolerogenic properties of G-CSF do not exclusively reside in its direct effect on DC, which in turn induce T-cell anergy, but also in its ability to generate a tolerogenic milieu in vivo, which is necessary for Tr1 cell induction and cannot be replicated in vitro.

This is probably due to the inflammatory milieu induced by cerulein that is necessary for the production of co-stimulatory signals needed for T cell activation that are not produced by pancreatic acini.

However, in permeabilized cells, modification of RyR function by CaMKII (or NOS) is assumed to be absent as the intracellular milieu is clamped at [Ca] below levels necessary for activation (see Supplementary material online) and comparable for CTRL and AF.

These data indicate that preexposure to ultrafine particles induces an inflammatory milieu promoting allergic immune responses rather than IFNgamma production necessary for microbial defense.

Thus, an adjuvant was necessary for us to produce a proinflammatory milieu.

One rationalisation for this vis a vis those studies may be that our assumption of a small stem cell fraction may effectively allow for a source of heterogeneity within the population that substitutes for the lack of milieu heterogeneity considered by Anderson et al to be necessary for expression of this phenotype.