Sentence examples for milieu contains from inspiring English sources

It is reasonable to assume that the in vivo milieu contains factors that promote the maturation of the transplanted cells.

The data suggest that the post-PDT tumour milieu contains the necessary components to establish effective IL-6 trans-signalling, thus providing a means for more effective tumour control.

Given the fact that the in vivo tumour milieu contains copious amounts of IL-6 after PDT and macrophages are a component of the PDT-induced host cell infiltrate (Gollnick et al, 1997; Henderson et al, 2004), these findings argue for a possible role of sIL-6R α and IL-6/sIL-6R α complex in PDT-treated tumours.

The post-PDT tumour milieu contains abundant amounts of IL-6 and other inflammatory mediators (Gollnick et al, 2003) to which surviving cells within the treatment field do not respond directly because of PDT-induced degradation and inactivation of their membrane-bound IL-6R α.

Furthermore, FK866 promoted tubular cell apoptosis in an inflammatory milieu containing the cytokines TNFα/IFNγ.

These findings suggest that in the injured mucosa, the pro-inflammatory milieu containing TNFα and PAF sets the stage for reparative events mediated by PAFR signaling.

The differentiation of naïve T cells into the Th17 phenotype has been shown to be facilitated by the presence of a cytokine milieu containing a combination of TGFβ and IL-6 [15, 15].

Based upon the published literature, particularly the large collection of in vitro work demonstrating improved cellular response, there is little doubt that the growth factor milieu contained within PRP has the potential to be highly beneficial to bone regeneration.

Naïve CD4+ T cells can be differentiated in vitro into IL-17-producing effector (Th17) cells in a cytokine milieu containing anti-IFN-γ, anti-IL-4, anti-IL-1β, anti-IL-6 and anti-IL-23 antibodies [ 25, 26].

"Alternatively activated" M2 microglia, such as induced in a milieu containing high IL-4 or IL-13 levels, have anti-inflammatory and tissue regenerative activities, which are mediated by cytokines such as IL-4, IL-10, or TGF- β and repair factors such as insulin-like growth factor, arginase-1, or chitinase-like-1.

To study the role that T cells play in a milieu that contains a human transgene (HLA DRB1*0101) that correlates with susceptibility to human rheumatoid arthritis (RA), a double-transgenic (DR1-TCR) Tg mouse was developed.