The composition of the CF airway milieu drives adaptations in neutrophils, and in turn, these adaptations influence this pathological microenvironment.
Previously, we proposed a parameter, the %chSp, to extract species-specific information that may be related to the cellular milieu and niche adaptation [ 4].
In our case, protein sequences of orthologs presented different values in each of the five physico-chemical series of values, that reflected the vast amount of specific changes in each ortholog and species, possibly responding again to the intracellular milieu and niche adaptation.
Matrix proteins not only allow anchorage of hepatocytes but also induce intracellular signaling pathways, thereby enabling sensing of the extracellular milieu with subsequent cellular adaptation to the environment.
The long-term objective is not assimilation or adaptation to milieus traditionally closed to women, but rather an articulation of individual parameters and active participation in a nuanced art public".
Clooney, in fact, reps a successful adaptation to his milieu.
The human nose is the primary reservoir of S. aureus, and evolution of the species was probably driven by adaptation to this milieu.
The study aims to test the hypothesis that the systemic inflammatory response after vascular intervention influences the local milieu responsible for vascular repair and adaptation.
Alternating replication in vertebrate and arthropod organisms would impose contrasting selective forces, where fitness increase in a given host cell type leads to fitness decrease in the other, generating a scenario of viral sub-optimal adaptation in each host milieu.
Phylogenetic data demonstrated that although PTH plays a key role in the development of bony skeleton, 83 PTH-like peptides and their receptors occurred before the transition from an aquatic to a terrestrial environment and not as adaptation to calcium-depleted milieu.
