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Initial laboratory values included mildly increased levels of bilirubin, alkaline phosphatase, and aspartate aminotransferase, and mild transaminitis with an increased level of alanine aminotransferase (Table 1).
We indeed found PS1 knockdown clones showed increased PS2 levels compared to non-target shRNA control lines while PS2 knockdown clones had mildly increased levels of PS1 compared to control lines (Figs. 2A and 2C).
The investigators observed mildly increased levels of Ang-1 protein in CDH lungs compared with controls during late development, using a nitrofen-based mouse model (Chinoy et al., 2002).
Laboratory studies revealed anemia (hemoglobin 95 g/L, reference value 120 160 g/L) with normal mean corpuscular volume (97.5 fL) of red blood cell, positive Sudan III staining of the stool, mildly increased levels of serum creatinine (120 μM, reference value 59 104 μM).
Similar(56)
Chloroquine exposure for 6 h, but not 30 h, mildly increased RTP801 levels (Supplementary Figure S1).
The addition of IGF-1 again mildly increased eGFP levels over T3-alone, while T3+Dex mildly, but significantly, increased TMRM accumulation.
We demonstrate that two out of three cancer-associated TERT mutations caused no effect and only the most prevalent promoter mutations mildly increased TERT levels in hESCs, which did not result in significantly increased telomerase activity.
As compared with subjects with normal eGFR, those with mildly reduced eGFR had increased levels of both CRP and TRX.
In conclusion, subjects with mildly decreased eGFR showed increased levels of biomarkers for inflammation and oxidative stress.
Given the mildly acidic pH of the TGN [37] [38], increased levels of copper in this compartment would lead to enhancement of Aβ toxicity and result in more severe Aβ-induced phenotypes, possibly through the induction of oxidative stress.
We showed the increased levels of CRP and TRX in subjects with mildly reduced eGFR.
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