Sentence examples for mildly fixed from inspiring English sources

These methods include visualizing microtubules in native and mildly fixed cytoskeletons from cultured cells, ciliate and flagellate protozoans and in living tumor cells, purification of tubulin from tumor cell lines and measurement of its taxoid binding capacity.

Although some of FAs are positive for TIAR, this typical SG marker readily dissociates from FAs following RNase digestion of cell extracts or mildly fixed cells, while this treatment has no effect on TIAR associated with SGs.

We first analyzed 10 single CellSearch/DEPArray-derived WBCs of nine patients and noted a higher derivative log2 ratio spread (DLRS) in our single WBC samples (mean 1.28, range 0.64 2.08), as compared to previously published single cell aCGH experiments with unfixed or mildly fixed cells (Czyz et al, 2014).

In general, pre-embedding labeling methods (typically a sample is mildly fixed, permeabilized and labeled by primary reagents before it is embedded and sectioned) can achieve more efficient labeling; post-embedding methods provide better preservation, while the Tokuyasu method often provides the best compromise (Griffiths 1993).

Echocardiographic parameters analysed were: valve morphology (normal or thickened), valve mobility (normal, mildly-, moderately-, severely diminished, fixed), valve regurgitation (none, I IV/IV), valvular stenosis and atrial/ventricular dimensions.

Bottlenecks can cause a rapid loss of genetic variation, fixing mildly deleterious alleles and increasing the degree of inbreeding, thereby reducing the adaptive potential of the population [ 6- 9].

This allows mildly deleterious mutations to be fixed in the population with a high probability.

Alternative mildly deleterious alleles can become fixed within diverging populations due to the effects of genetic drift.

With a small population size, natural selection is inefficient, and mildly deleterious mutations can be fixed even when they would not occur in a large population.

This means that only neutral and mildly deleterious mutations will be fixed at an intra-individual level but not deleterious mutations, as is observed in the majority of mitochondrial diseases in which the mutant type never reaches intra-individual fixation.

The mechanism explaining the mildly lower FIX protein expression from the FIXR338L vector is under investigation.