Sentence examples for mildly compromised from inspiring English sources

We demonstrate that dermal fibroblasts from PD patients display flawed nucleotide excision repair (NER) capacity and that Ercc1 mutant mice with mildly compromised NER exhibit typical PD-like pathological alterations, including decreased striatal dopaminergic innervation, increased phospho-synuclein levels, and defects in mitochondrial respiration.

Rescue activity was mildly compromised by deletions of 22, 32, 40, and 50 amino acids.

Interestingly, the number and distribution of RTP foci were only mildly compromised by repression of scpAB expression at early stages of outgrowth.

Interestingly, long-term HSC (LT-HSC) function was not compromised [11] or mildly compromised [12] when the Scl deletion occurred post-transplantation.

In this scenario, which remains to be tested, complex I deficiency could be explained by decreased expression levels of correctly spliced NUBPL, in combination with mildly compromised functionality due to the missense mutation.

Thus, while we view the combination of capecitabine and radioembolization as safe in this conservatively defined patient population, caution may be warranted in the utilisation of this combined modality approach in patients with mildly compromised liver function.

Unlike the other SGAs, paliperidone is almost not affected by the enzymes involved in hepatic metabolism and is excreted primarily (60%) in the unchanged form into the urine, allowing the use of this drug in patients with mildly or moderately compromised hepatic function [ 16].

Cross-linking of PEG-D was previously determined to be severely compromised under mildly acidic conditions.

However, our lab recently reported that the oxidative cross-linking of dopamine was strongly affected by pH and its adhesive performance was severely compromised under mildly acidic physiological pH (i.e., 5.7 6.7).

Affected children may demonstrate a spectrum of abnormalities, from appearing normal or mildly affected to being severely compromised, depending on the degree of mitochondrial dysfunction and the extent of tissue involvement.

Vice versa, vascular branching, which was severely compromised by endothelial NRP1 loss, ABL inhibition or CDC42 inhibition, was only mildly affected in Nrp1 Y297A/Y297A P6 retinas.