Sentence examples for milder phenotype of from inspiring English sources

Alternatively, the milder phenotype of the constitutive miR-143/145 KO mice could partly be due to compensatory mechanisms.

We could not detect an additional copy of GPR126 in the zebrafish genome which could explain the milder phenotype of the gpr126 st49) allele.

This probably reflects a milder phenotype of AR-CGD, and hence an extensive immunological work-up at a later age, and not a bias towards earlier screening of boys for CGD.

The milder phenotype of dmpk−/− mice compared to MKR mice is consistent with a mechanism involving a reduction of InsR and IGF-1R function rather than full inactivation of these receptors.

For instance, the prevalence of fetal alcohol syndrome disorder is estimated at 1 per 1000, but this condition is far less commonly identified in the UK than in North America, where a milder phenotype of 'fetal alcohol spectrum disorder' is recognised and estimated to be nine times as common [7].

However, the functional impacts were less severe, in line with the milder phenotype of the patient (see Fig 2).

This is consistent with the finding that inactivation of only the mitochondrial genome by ethidium bromide treatment causes the milder phenotypes of slow growth and reduced brood size [25].

In contrast to the milder phenotypes of sua7 -Pol II GOF strains, Pol II LOF mutants were exquisitely sensitive to defects in TFIIB, as widespread synthetic lethality or sickness was observed between sua7 alleles and Pol II LOF mutants.

The relatively mild phenotype of these mice mimics patients with milder PEX7 defects, and highlights the skeleton and lens as sensitive markers of plasmalogen deficiency.

Since we observed only small differences in behavior between Per2−/− and Per2+/+ mice, we expected to observe a mild phenotype of Per1-luc expression in the Per2−/− SCN.

The relatively mild phenotype of P19[Gli/EnR] cells is consistent with previous reports showing that Shh signaling is not essential for the neural tube development [1], [17], [18].