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On the other hand, when a cell was transfected with a lower dose of DLC1, DLC1 would extinguish most of the stress fibers and stress fiber-linked focal adhesions but spare some focal adhesions not linked to stress fibers and result in a milder cell collapse (Figure S1A).
Patients with tremor-dominant Parkinson's disease have milder cell loss in the substantia nigra pars compacta (particularly in the lateral portion) and in the locus coeruleus than patients with non-tremor Parkinson's disease (Paulus and Jellinger, 1991; Jellinger, 1999).
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In contrast, CoCl2-insulted differentiated PC12 cells developed mild cell body swelling and some cells shrunk the dendritic networks even lost neurites demonstrating round shape (Figure 1-C).
Mild cell and tissue injuries, mainly in forms of cellular edema and degeneration, were found in liver (Fig. 5B) and kidney (Fig. 5C) from mice infected with the mutant virus.
Conversely, expression of the small GTPase Rheb, which activates TOR signaling, leads to a mild cell size increase under conditions of nutrient abundance and to a stronger one under starvation, as has been reported previously [18], [19].
Our results show that treatment of HCT116) and SW480) cells with 30 μg/mL cetuximab, which previously showed a mild cell growth inhibition, induced mild cell apoptosis, with values of 9.1% and 6.3%, respectively.
Only when the TMZ concentration was elevated to 100 μM did T98G cells show a very mild cell death response.
Loss of TolA causes mild cell chaining, observed here in the longer Δ tolA cells possessing multiple points of constriction (Δ tolA, cell width plot).
Overall these results suggest that DT compounds induce a stress response unlike docetaxel, and induce a mild cell cycle arrest resulting in a late signature of apoptosis.
Motor system pathology was characterized by mild cell loss and tau pathology in giant pyramidal cells of Brodmann area 4, as well as mild loss of axons and myelin in the corticospinal tract.
As shown in Figure 5, mice immunized with the BCR/ABL-pIRES-hIL-2 (d) caused moderate cell inflammatory cell infiltration, and those immunized with BCR/ABL-pIRES (c) and pIRES-hIL-2 (e) induced mild cell infiltration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com