There is also some mild seasonal variability with reduced outpatient volumes in the early August and in the last week of December.
34, 36 Although subject to high levels of variability, mild cognitive deficits have been reported, including deficits in spatial memory, conditioned fear, and novel object recognition.
The mild group showed less variability in the timing of the sequence that is in accord with a more stable representation of the action.
It is therefore possible that patients with mild hypercortisolism have less variability in UFC levels than these patients with moderate-to-severe hypercortisolism.
The sample size is especially relevant when considering that, in many cases, changes in DNA methylation are mild and the biological variability may be high.
Most of the rheumatic disorders are heterogeneous diseases with a clinical spectrum that ranges from mild to severe, and variability in secondary organ system involvement (for example, heart failure).
In this regard, it is interesting to note that the moderate group although more variable than the mild group did show a decrease in variability with the first two-thirds of practice.
However, it is important to note that this loss of genetic variability was relatively mild, since after 40 generations of laboratory adaptation AR and TW populations retained, respectively, 95%and90%0% of their initial genetic diversity.
The secondary objectives were evaluation of changes in glucose variability, frequency of mild and/or severe hypoglycemic events, changes in QoL, efficacy of CGM in patients treated by CSII and MDI, and efficacy of CGM in optimally educated patients versus nonoptimally educated patients.
Moreover, upon retesting, some positive lines had stronger migration defects, whereas others were milder; this suggests slight inherent variability of knockdown efficiency.
