Sentence examples for mild toxicity in from inspiring English sources

This dose caused severe cholinergic signs of toxicity and lethality in wild-type mice, but caused no deaths and only mild toxicity in transgenic animals.

Gefitinib is a targeted drug with single-agent activity, and has shown mild toxicity in platina pretreated patients with NSCLC (Fukuoka et al, 2003; Kris et al, 2003).

S-1 is an oral fluoropyrimidine derivative that has demonstrated excellent efficacy with mild toxicity in patients with metastatic PC (Furuse et al, 2005).

Overall, gefitinib 250 mg day−1 showed reasonable efficacy and mild toxicity in these studies, and appears to be a valuable treatment option for elderly patients.

The combined treatment with CRIS and MSO exhibits only a mild toxicity in vivo as shown by a minor decrease in body weight in nude mice, confirmed in NSG mice (results not shown).

One possible explanation for milder toxicities in the NAC + IMRT group may be that NAC was likely to reduce primary tumor volume for patients with intracranial invasion, and re-planning of the delineation for tumor volume after NAC could better protect critical normal tissue and reduce IMRT-associated adverse events [ 33].

Only mild toxicity was observed in patients with steady-state plasma concentrations below 1.5  μ M (3.0 mg m−2 h−1).

Heavy ion therapy using carbon ions however, so far only showed a mild toxicity profile even in dose escalation and hypofractionation [ 4].

Based on these results, the patient received 4 cycles of Bleomycin, Etoposide and Platinum chemotherapy experiencing only mild toxicity and resulting in complete ongoing clinical and biochemical remission.

Gemcitabine's mild toxicity profile, both in terms of haematological toxicity and visceral side effects, and novel mechanism of action have encouraged its use in combination with traditional agents, such as cisplatin.

Treatment with the indolinones resulted in mild toxicity effects for the treatment with BI1, BI2 and BI3 at high concentrations and almost no toxicity for BI4 and BI5 (Fig. 5b).