Sentence examples for mild toxic effects from inspiring English sources

These findings are consistent with the hypothesis that highly elevated UBB+1 expression might have mild toxic effects that could interfere with the normal neuronal function [ 42].

We assume that due to the mild toxic effects of oxLDL in normal fibroblasts, ATM induction triggers an activation of cell cycle checkpoints and not apoptotic cascade activation.

They reported that E. hirta leaves methanol extract exhibited mild toxic effects in mice at a dose of 5000 mg/kg body weight.

Both, the MTT and the Trypan blue exclusion assay, and the appearance of condensed chromatin, demonstrated that oxLDL exhibited mild toxic effects on VA13 cells, with PARP cleavage and caspase 3 activation not being detected.

Mild toxic effects are difficult to determine in critically ill patients without a randomized controlled design due to the complexity of critical illness and its associated multiple drug use and also because tobramycin leakage during the first ICU day was already associated with oliguria at ICU admission, before any tobramycin was administered.

As a matter of fact, the weekly EPI schedule was chosen because we had previously demonstrated that this drug can be administered weekly for long periods without giving rise to more than mild toxic effects (Francini et al, 1993; Petrioli et al, 2002).

Without radiation, PARP1 silencing or inhibition appeared to exert a mild toxic effect against U87MG-EGFRvIII cells that was not seen with U87MG cells.

Does LCA act as a pharmacological agent by binding a specific receptor in yeast or does it increase longevity by stimulating stress response due to its mild toxic effect (by hormesis)?

In the absence of serum, the positively charged FFSNPs were accumulated into the HOB cells more strongly than negative ones which was accompanied by a mild toxic effect of the positively charged FFSNPs.

Injection of GP-AC nanoparticles and the mixed licorice-aconite decoction, respectively, caused mild recoverable toxic effects and no death, while the aconitine, particle-free GP-AC mixture and aconite decoction induced sever toxic effects and 100%% death.

Another study has shown mild adverse toxic effects on reproductive endpoints and liver function in adult rats, as well as abnormal developmental effects in offspring when supplemented with Zn at concentrations of 7.5, 15, and 30 mg/kg [ 22].