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The majority of the adverse events were mild to intermediate and spontaneously alleviated or recovered.
Thus, the data of our study must be interpreted with caution when using propofol at mild to intermediate doses in obstructive jaundice.
Regarding serum markers, none of these serum markers can adequately distinguish intermediate fibrosis stages, even though the progression from mild to intermediate fibrosis is an important predictor of further fibrosis progression.
IS in nondiabetic NOD mice averaged 0.454 ± 0.052 (Additional file 1 [Supplementary table 2]), representing mild to intermediate insulitis expressed on a scale from 0 (no inflammation) to 1 (all islets are to a large extent invaded by lymphocytes).
In contrast, maintenance of a multipotent HSC state was associated with mild increases in Wnt signal activation, while myeloid differentiation was only promoted by mild to intermediate increases in activation, and high to very high increases in Wnt activation were detrimental to murine HSC self-renewal and differentiation (Luis et al., 2011).
However, there was a very clear difference between the formation of acetic acid and formic acid in the sense that the concentrations of formic acid were rather similar regardless of whether the pretreatment conditions were mild, intermediate or severe, while the concentrations of acetic acid increased very much when the pretreatment changed from mild to intermediate conditions.
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More generally, given how important severity estimates are early on in an outbreak and since, unfortunately, there is currently no real alternative to the pyramidal approach in a context of mild-to-intermediate sCFR, in the future it will be important to develop studies that can be conducted in parallel with pyramidal severity estimation to assess the validity and bias in the estimates.
The presence of intermediate leptospiral DNA and the absence of more serious symptoms of leptospirosis (jaundice, hemorrhages, renal failure) in our study are consistent with reports of mild disease linked to intermediate Leptospira spp., such as L. licerasiae in Peru (11 ), L. wolffii in Thailand (14 ), and L. inadai (12 ).
PanIN-2 lesions (intermediate-grade PanIN) show mild to moderate cytological and architectural atypia (e.g., nuclear pleomorphism, nuclear crowding, and nuclear hyperchromasia) with frequent papillae [ 6, 15].
It is usually homogenous with intermediate signal on T1 and high signal on T2 with mild to moderate enhancement (Fig. 7).
The cells were intermediate in size and round to oval in shape with mild to moderate basophilic cytoplasm without granules.
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