Sentence examples for mild stress models from inspiring English sources

Examples are NKP-608, which has been shown to have anxiolytic-like and antidepressant-like properties in social interaction and chronic mild stress models (File 2000; Papp et al. 2000; Vassout et al. 2000), and FK-888 and WIN51,708, which produced anxiolytic-like effects in mouse and rat elevated plus-mazes, respectively (Teixeira et al. 1996; Nikolaus et al. 1999).

We reported previously that animals with depression (using olfactory bulbectomy or unpredictable chronic mild stress models) elicited severe nociceptive behaviours and had increased plasma levels of substance P [9, 10].

Moreover, the sucrose preference test has been used extensively to measure anhedonia, a core symptom of depression, in mild stress models of depression [ 38- 40].

Electroconvulsive stimulation (ECS) has previously been shown to reverse a depression-like state in the chronic mild stress model of depression (CMS), but the effect of ECS on cognition has not previously been investigated.

Researchers use these tests to evaluate the success of establishing depression in an animal model, such as in an unpredictable chronic mild stress model [16].

In this respect, Schweizer and coworkers [30] further clarify how different inbred strains of mice can have very different vulnerabilities to the chronic mild stress model of depression in both behavioral and physiological parameters, thus offering an invaluable tool to understanding G×E interaction in stress-induced disturbances.

We used the chronic unpredictable mild stress model to investigate the role of Ace in stress-induced signs of neurodegeneration.

In this respect, the chronic mild stress model could complement genetic AD models because the CUMS model solely relies on endogenously expressed proteins.

In this study, we evaluated the anti-depressive effects of NS based on behavior tests in a forced swimming test and a chronic mild stress model.

D'Audiffret et al. [ 61] applied the unpredictable chronic mild stress model in mice to interrogate the association between depressive disorders and peripheral vascular disease.

In order to evaluate the antidepressant efficacy of melatonin treatment, Detanico et al. [ 80] utilized a chronic mild stress model in the mouse.