Sentence examples for mild stress model from inspiring English sources

Researchers use these tests to evaluate the success of establishing depression in an animal model, such as in an unpredictable chronic mild stress model [16].

Electroconvulsive stimulation (ECS) has previously been shown to reverse a depression-like state in the chronic mild stress model of depression (CMS), but the effect of ECS on cognition has not previously been investigated.

In this respect, Schweizer and coworkers [30] further clarify how different inbred strains of mice can have very different vulnerabilities to the chronic mild stress model of depression in both behavioral and physiological parameters, thus offering an invaluable tool to understanding G×E interaction in stress-induced disturbances.

We used the chronic unpredictable mild stress model to investigate the role of Ace in stress-induced signs of neurodegeneration.

D'Audiffret et al. [ 61] applied the unpredictable chronic mild stress model in mice to interrogate the association between depressive disorders and peripheral vascular disease.

In order to evaluate the antidepressant efficacy of melatonin treatment, Detanico et al. [ 80] utilized a chronic mild stress model in the mouse.

We reported previously that animals with depression (using olfactory bulbectomy or unpredictable chronic mild stress models) elicited severe nociceptive behaviours and had increased plasma levels of substance P [9, 10].

Moreover, the sucrose preference test has been used extensively to measure anhedonia, a core symptom of depression, in mild stress models of depression [ 38- 40].

Data from animal models (e.g. the chronic mild stress (CMS) model) have indicated that depression exascerbates stress reactivity, and is associated with autonomic and cardiovascular dysfunction, including reduced heart rate variability (HRV) as well as elevated heart rate (HR) and sympathetic cardiac tone [ 11- 13].

The present study was designed to evaluate the potential antidepressant-like activity of total furocoumarins of P. corylifolia (TFPC) in the chronic mild stress (CMS) model of depression.

The present study was designed to evaluate the antidepressant-like effects of thymol on a chronic unpredictable mild stress (CUMS) model of depression in mice and explore the underlying mechanisms.