Sentence examples for mild platelet dysfunction from inspiring English sources

Mild platelet dysfunction occurs at temperatures <35°C, and some inhibition of the coagulation cascade develops at temperatures <33°C.

Temperatures below 35°C can in some cases (but not in all patients, see below) induce mild platelet dysfunction and sometimes a mild decrease in platelet count.

At temperatures below 35°C some patients may begin to have mild platelet dysfunction (although in most patients this will occur only at lower temperatures).

Given their essential role in regulating actin dynamics, it was surprising that the deletion of the genes encoding Mena or VASP in mice resulted in only mild neuronal or platelet dysfunction [ 13- 16].

LAD3 or LAD1 variant is characterized by the combination of a relatively mild LAD phenotype and platelet dysfunction in the presence of normal integrin expression.

Thus, normal PFA CT results can be used with some confidence to exclude severe vWD or severe platelet dysfunction but would not exclude a possible mild vWF deficiency or mild platelet disorder.

These abnormalities include anaemia, bleeding and granulocyte and platelet dysfunction.

Whilst platelets also contain ROK, actin-myosin-dependent platelet contraction does not appear to be mediated by ROK inhibition of MLCP, and septic shock-induced platelet dysfunction does not appear to be a consequence of platelet contractile dysfunction.

Hypothermia also induces temporary thrombocytopenia (28% drop at 32°C) and platelet dysfunction [36, 37].

Management options for platelet dysfunction in trauma patients are controversial, expensive, and potentially harmful.

As pathophysiological reasoning, hypothermia induces platelet dysfunction and impairs the plasmatic coagulation system, especially below a threshold of 33°C.