Sentence examples for mild phenotypes in from inspiring English sources

When modifier mutations are co-expressed in Aβ42-expressing flies, the distribution of phenotypes is shifted to more mild phenotypes in the case of a suppressor, or more severe phenotypes in a case of an enhancer (Fig. S1A C and Table 1).

Comparison among highly homologous coagulation serine proteases indicate that additive or compensatory pleiotropic effects on secretion and function by carboxyl-terminal mutations produce life-threatening or mild phenotypes in the presence of similarly reduced protein amounts.

In contrast to animals, where HIRA is required for fertilization and early development, loss of function of HIRA in Arabidopsis causes mild phenotypes in the adult plant and does not perturb sexual reproduction and embryogenesis.

Since HR6A and HR6B differ at only 8 amino acid positions, it is thought that the proteins perform redundant functions, and single gene mutations therefore yield relatively mild phenotypes in mouse [ 25, 26].

While the relatively mild phenotypes in human cells may be due to the presence of residual proteins in siRNA experiments, genetic analysis in Arabidopsis showed that the CST complex, while important for proper telomere maintenance, is not absolutely essential for survival.

Most frequent were abdominal malformations (93.3%; n=30 cuticles), ranging from mild phenotypes in which the abdomen was constricted ("small abd", 13.3%, not shown) to cuticles which showed an inversion of abdominal segments into the interior of the cuticle (abdomen inside-out: "Abd i-o", 36.6%; Figure 2C).

Truncation at W466 has reportedly resulted in a mild phenotype in human but causes a severe phenotypic effect in goat.

At 14 days of age, instead, all TTR flies showed signs of retinal degeneration, varying from a mild phenotype in TTRwt flies to strong degeneration in TTR-A flies, especially in those carrying two TTR-A copies.

From our point of view it is therefore not at all surprising that the FEZ1-/ mice had such a mild phenotype in comparison to the UNC-76 -/- worm [32].

The observed relatively mild phenotype in the FEZ -/- mice may be as well attributed to additional proteins interacting with FEZ2, which may interfere in the way of a dominant negative in FEZ1 specific functions, as to specific but not yet identified PPI for FEZ1.

Both mother and daughter had a very mild phenotype in comparison with typical patients with PHA1.