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Hence, a large "real-world" effectiveness study is needed to evaluate the benefits of early intervention with inhaled steroids in patients with mild, persistent asthma.
There is a need for further investigation into the true prevalence of mild persistent asthma in children and adolescents, and optimal treatment.
Limitations in asthma prevalence studies and difficulties in diagnosing pediatric asthma lead to uncertainty over the full extent of mild persistent asthma in children and adolescents.
Therefore, we aimed to determine the efficacy of augmented Yu Ping Feng San (aYPFS) as an add-on to oral montelukast compared with montelukast alone for treatment of mild persistent asthma in children.
It is unclear whether children with mild persistent asthma progress to more severe asthma, but the risk of severe asthma exacerbations seems to be unrelated to the symptom severity.
Clinical studies restricted to pediatric patients with mild asthma are limited, but available data do suggest substantial morbidity of mild persistent asthma in this population and support inhaled corticosteroid intervention.
Similar(21)
To compare the effect of inhaled budesonide given daily or as-needed on mild persistent childhood asthma.
The Swedish Search study is a multicenter investigation in which school-aged children (mean 12.6 ± 3.9 years) with problematic uncontrolled severe asthma were compared with age-matched peers with mild controlled persistent asthma (45).
Regular use of inhaled glucocorticoids may not abrogate the systemic Th2 type of inflammatory response in mild-moderate persistent asthma.
The study of asthma patients was a 12-month randomized controlled trial conducted in inhaled corticosteroid naïve adult patients with mild persistent to moderate persistent asthma that compared two inhaled corticosteroid treatments, triamcinolone acetonide hydrofluoroalkane and fluticasone propionate.
Most patients had moderate or severe COPD, and mild persistent or moderate persistent asthma.
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