A subsequent paper evidenced a moderate effectiveness of the 2008 2009 seasonal vaccines against pandemic A(H1N1) mild outcomes (VE = 42%, 29 53%) [31], while another one put forward an increased risk (odds-ratio = 2.45, 1.34 4.48) [32].
This association with protection was found to be especially apparent for severe disease as compared to milder outcome, as well as in the youngest and older populations.
As for NAC, the dominant up-regulation of upsC subtypes this compound causes may possibly confer protection to the host as expression of this subtype is correlated to milder outcome of disease and lower incidence of cerebral malaria.
CA16 associated HFMD has a milder outcome and a much lower incidence of severe complications [ 12].
In contrast, dietary supplements with a higher safety margin exert milder outcomes.
This association with protection was greater for severe disease as compared to milder outcomes.
Low five-minute Apgar score has been associated with increased risk of severe neurologic outcome, but data on milder outcomes, particularly in the long term, are limited.
Males with Klinefelter syndrome, like normal females, inactivate one of their two X chromosomes in each cell, perhaps explaining, at least in part, the relatively mild clinical outcome.
Of patients who had a mild clinical outcome (CEAP score, 1 to 3), 64% had a healthy contralateral limb, and the remaining 36% had mild to moderate disease.
Also mice vaccinated twice with 104 pfu but infected with the heterologous strain A/IND/5/05 had a mild clinical outcome of infection and recovered from infection.
