Based on our data, we propose that parapharyngeal extension should be subclassified as mild or extensive and that mild and extensive parapharyngeal extension should be classified as stage T2 and stage T4 disease, respectively.
Parapharyngeal extension in NPC should be subclassified as mild or extensive, which should be regarded as stages T2 and T4 diseases, respectively.
Detailed post-hoc analyses are as below: following either the mild or extensive stress, both ACTH and CORT reached the peak level at 1 hour in control and tg mice, and a significant difference (p<0.05) in both hormones was found between control-1-shock (n = 11) and control-36-shock mice (n = 11), indicating that the peak level was directly related to the intensity of the stress in control mice.
§By histologic examination, WNV antigen was absent, mild, moderate, or extensive.
While normal myocardium from humans and from chimpanzees are histologically quite similar (Fig. 1 uppermost panels), no human counterpart was observed of the mild, moderate or extensive IMF seen in chimpanzees (see Fig. 1 for an example of extensive fibrosis).
The extent of disease in those with interstitial lung disease (9 subjects) was stratified as either mild (5 subjects) or extensive (4 subjects) according to previously described methodology using high-resolution chest computerized tomography (HRCT) and forced vital capacity (FVC) criteria [57].
The OS, LRFS, and DMFS of patients with mild parapharyngeal extension were significantly higher than those of T3 patients, and patients with extensive parapharyngeal extension had OS, LRFS, and DMFS similar to those of patients with stage T4 disease; therefore, it seems reasonable that mild and extensive parapharyngeal extension should be classified as stages T2 and T4 diseases, respectively.
By contrast, the OS, LRFS, and DMFS of patients with extensive parapharyngeal extension were close to those of patients with T4 disease (P = 0.052, P = 0.193, and P = 0.115, resp .. Hence, mild and extensive parapharyngeal extension should be classified as stage T2 and T4 disease, respectively.
Dr John-Louis Vincent of the Erasme Hospital, Brussels, Belgium, presented an overview of the study of sepsis so far and suggested that we move to a new definition, namely the IRO staging system: I for infection (localised, generalised or extensive), R for response (limited, extensive or excessive) and O for organ dysfunction (mild, moderate or severe), akin to the TNM staging of cancers.
Histologic analysis revealed mild to extensive multifocal histiocytic infiltration of the jejunum, ileum, colon and cecum.
The severity of footrot was scored using the system described by Egerton and Roberts [ 13] on a scale of 1 to 4 (scores 1-2 early stages of footrot with mild to extensive interdigital dermatitis and scores 3-4 extensinterdigitalital dermatitis plus under-running of hoof horn) for acute lesions and lesion scores 3-4 for chronic lesions.
