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Only mild modulatory effects of intranasal insufflation of CO2 at flow rates of 1 l/min could be seen in a human model of TRPV1 mediated activation of nociceptive trigeminal neurons which is in line with previous studies.
Although mild modulatory effects of low-flow intranasal CO2 could be seen in this human model of TRPV-1 mediated activation of nociceptive trigeminal neurons, utility is limited as observed changes in pain ratings are clinically non-significant.
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Additionally, the study will shed light on the possible immune modulatory effects of NAC treatment.
Multiple studies have suggested that these modulatory effects of statins may be therapeutic in systemic autoimmune disorders [16].
Although these modulatory effects are partially understood, direct cell-to-cell contact and soluble factors are relevant [90].
Accordingly, we examined the modulatory effects of brain nAChR systems on NMDAR antagonist-induced effects.
Conversely, σ1 receptor antagonists are considered antiproliferative, antiangiogenic and to have modulatory effects on opioid analgesia [15 17].
Within these regions we investigated the modulatory effects attention and the effect of task upon these.
Spinal learning also induces modulatory effects that alter the capacity for learning.
Collectively, these data suggest that PACAP38 and VIP might have modulatory effects on nociceptive processing in the human skin.
Moreover, both agmatine and lithium have modulatory effects on α2-adrenoceptors.
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